Effects of acetylsalicylic acid in stroke patients evidence of nonresponders in a subpopulation of treated patients
KH Grotemeyer - Thrombosis research, 1991 - Elsevier
Platelet reactivity (PR) was tested two and 12 hours after acetylsalicylic acid (ASA) intake in
82 stroke patients, aged 59±14 years (33 female and 49 male). 10% of these patients
showed a pathologically enhanced PR at least two hours after intake of 500 mg ASA (=
primary ASA-nonresponder (PNR)). Only 10 hours later, a further 26% of these ASA treated
patients exhibited a pathological platelet reactivity (1.25)(= secondary ASA-nonresponder
(SNR)). Single ASA dosages of 500 mg or 200 mg were of identical effectiveness. Additional …
82 stroke patients, aged 59±14 years (33 female and 49 male). 10% of these patients
showed a pathologically enhanced PR at least two hours after intake of 500 mg ASA (=
primary ASA-nonresponder (PNR)). Only 10 hours later, a further 26% of these ASA treated
patients exhibited a pathological platelet reactivity (1.25)(= secondary ASA-nonresponder
(SNR)). Single ASA dosages of 500 mg or 200 mg were of identical effectiveness. Additional …