NK cell receptors in antiviral immunity
JM Moser, AM Byers, AE Lukacher - Current opinion in immunology, 2002 - Elsevier
JM Moser, AM Byers, AE Lukacher
Current opinion in immunology, 2002•ElsevierAn array of inhibitory and activating receptors initially identified on NK cells are also
expressed by conventional CD8+ αβ T cells. New evidence strongly implicates these 'NK
cell receptors' in modulating NK cell and virus-specific CD8+ T cell responses against a
variety of viral infections. Precise regulation of NK cell and T cell responses by these
receptors optimizes antiviral immunity while preventing immunological bystander pathology
and autoimmunity.
expressed by conventional CD8+ αβ T cells. New evidence strongly implicates these 'NK
cell receptors' in modulating NK cell and virus-specific CD8+ T cell responses against a
variety of viral infections. Precise regulation of NK cell and T cell responses by these
receptors optimizes antiviral immunity while preventing immunological bystander pathology
and autoimmunity.
An array of inhibitory and activating receptors initially identified on NK cells are also expressed by conventional CD8+ αβ T cells. New evidence strongly implicates these ‘NK cell receptors’ in modulating NK cell and virus-specific CD8+ T cell responses against a variety of viral infections. Precise regulation of NK cell and T cell responses by these receptors optimizes antiviral immunity while preventing immunological bystander pathology and autoimmunity.
Elsevier
