Human tumor antigens recognized by T cells

PF Robbins, Y Kawakami - Current opinion in immunology, 1996 - Elsevier
PF Robbins, Y Kawakami
Current opinion in immunology, 1996Elsevier
The ability of tumor-reactive T cells to mediate in vivo tumor regression has been
demonstrated in murine tumor models and by the clinical responses to adoptive
immunotherapy with tumor-infiltrating lymphocytes isolated from human melanomas.
Investigations carried out in the past several years have resulted in the isolation of a number
of the genes encoding antigesn recognized by melanoma-reactive T cells. The ability of
these products to serve as tumor regression antigens has now begun to be evaluated in …
The ability of tumor-reactive T cells to mediate in vivo tumor regression has been demonstrated in murine tumor models and by the clinical responses to adoptive immunotherapy with tumor-infiltrating lymphocytes isolated from human melanomas. Investigations carried out in the past several years have resulted in the isolation of a number of the genes encoding antigesn recognized by melanoma-reactive T cells. The ability of these products to serve as tumor regression antigens has now begun to be evaluated in clunical vaccine trials.
Elsevier