Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia

TR Parr Jr, RA Moore, LV Moore… - Antimicrobial agents and …, 1987 - Am Soc Microbiol
TR Parr Jr, RA Moore, LV Moore, RE Hancock
Antimicrobial agents and chemotherapy, 1987Am Soc Microbiol
The measured outer membrane permeability of Pseudomonas cepacia to the beta-lactam
nitrocefin was low: approximately 10 times less than that of Escherichia coli and comparable
to that of Pseudomonas aeruginosa. The purified P. cepacia porin demonstrated an average
single channel conductance in 1 M KCl of 0.23 nS.
The measured outer membrane permeability of Pseudomonas cepacia to the beta-lactam nitrocefin was low: approximately 10 times less than that of Escherichia coli and comparable to that of Pseudomonas aeruginosa. The purified P. cepacia porin demonstrated an average single channel conductance in 1 M KCl of 0.23 nS.
American Society for Microbiology