Pituitary adenylate cyclase-activating polypeptide (PACAP) is a highly conserved
neuropeptide and widely expressed in both brain and peripheral tissues, including several
reproductive organs (eg, testis and ovary). PACAP stimulates syntheses of several sexual
hormones and steroids, suggesting it has possible roles in reproductive function. In this
study, the role of PACAP in female reproductive functions such as fertility, mating behavior
and maternal behaviors were investigated by using mice lacking PACAP (PACAP−/−) …