Sequential studies on the pathophysiology of glycerol-induced acute renal failure
HJ Reineck, GJ O'Connor, MD Lifschitz… - The Journal of …, 1980 - translationalres.com
The role of volume depletion and renal ischemia in the development of renal functional
impairment in glycerol-induced ARF is not clear. This study was designed to evaluate the
role of volume depletion in this model by determining the hemodynamic and functional
alterations which occur between 3 and 18 hr after glycerol administration and the
reversibility of these changes in response to Ringer loading. Three hours after glycerol, C In
and RBF, measured by flowmeter, were reduced 70% and 52%, respectively, in comparison …
impairment in glycerol-induced ARF is not clear. This study was designed to evaluate the
role of volume depletion in this model by determining the hemodynamic and functional
alterations which occur between 3 and 18 hr after glycerol administration and the
reversibility of these changes in response to Ringer loading. Three hours after glycerol, C In
and RBF, measured by flowmeter, were reduced 70% and 52%, respectively, in comparison …