Impact of American Society of Clinical Oncology/College of American Pathologists guideline recommendations on HER2 interpretation in breast cancer

SS Shah, RP Ketterling, MP Goetz, JN Ingle… - Human pathology, 2010 - Elsevier
Accurate assessment of human epidermal growth factor receptor 2 is critical for the
management of patients with breast cancer. We set out to study the impact of the 2007
American Society of Clinical Oncology/College of American Pathologists guidelines on the
interpretation of human epidermal growth factor receptor 2 IHC results and its correlation
with fluorescence in situ hybridization results. Invasive breast carcinomas with IHC
HercepTest 3+ were retrieved from the archive of Mayo Clinic Rochester. The human …