Selectivity of the endothelial monolayer: effects of increased permeability
A Siflinger-Birnboim, JA Cooper, PJ Del Vecchio… - Microvascular …, 1988 - Elsevier
We investigated the mechanism of thrombin-induced increases in endothelial monolayer
permeability by examining the effect of thrombin on the molecular sieving characteristics of
the endothelial monolayer and comparing the responses of arterial-and venous-derived
endothelial cell lines. Bovine pulmonary artery (BPA) and pulmonary vein (BPV) endothelial
cells were similarly harvested and cultured. The endothelial cells were grown to confluence
on gelatinized polycarbonate filters and the permeabilities to sucrose, albumin, and IgG …
permeability by examining the effect of thrombin on the molecular sieving characteristics of
the endothelial monolayer and comparing the responses of arterial-and venous-derived
endothelial cell lines. Bovine pulmonary artery (BPA) and pulmonary vein (BPV) endothelial
cells were similarly harvested and cultured. The endothelial cells were grown to confluence
on gelatinized polycarbonate filters and the permeabilities to sucrose, albumin, and IgG …
