Epithelial Na+ channel regulation by cytoplasmic and extracellular factors
OB Kashlan, TR Kleyman - Experimental cell research, 2012 - Elsevier
OB Kashlan, TR Kleyman
Experimental cell research, 2012•ElsevierElectrogenic Na+ transport across high resistance epithelial is mediated by the epithelial
Na+ channel (ENaC). Our understanding of the mechanisms of ENaC regulation has
continued to evolve over the two decades following the cloning of ENaC subunits. This
review highlights many of the cellular and extracellular factors that regulate channel
trafficking or gating.
Na+ channel (ENaC). Our understanding of the mechanisms of ENaC regulation has
continued to evolve over the two decades following the cloning of ENaC subunits. This
review highlights many of the cellular and extracellular factors that regulate channel
trafficking or gating.
Electrogenic Na+ transport across high resistance epithelial is mediated by the epithelial Na+ channel (ENaC). Our understanding of the mechanisms of ENaC regulation has continued to evolve over the two decades following the cloning of ENaC subunits. This review highlights many of the cellular and extracellular factors that regulate channel trafficking or gating.
Elsevier