[HTML][HTML] Cancer genetics: tumor suppressor meets oncogene
ER Fearon, CV Dang - Current Biology, 1999 - cell.com
ER Fearon, CV Dang
Current Biology, 1999•cell.comCancer genetics: Tumor suppressor meets oncogene: Current Biology Skip to Main Content
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Abstract
The adenomatous polyposis coli (APC) tumor suppressor protein is inactivated by mutations in the majority of colorectal cancers. A recent study has revealed that alterations in the APC signaling pathway can result in the transcriptional activation of the c-MYC gene.
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