[HTML][HTML] Clinical implications of intestinal stem cell markers in colorectal cancer
MLM Espersen, J Olsen, D Linnemann, E Høgdall… - Clinical colorectal …, 2015 - Elsevier
Colorectal cancer (CRC) still has one of the highest incidence and mortality rate among
cancers. Therefore, improved differential diagnostics and personalized treatment are still
needed. Several intestinal stem cell markers have been found to be associated with CRC
and might have a prognostic and predictive significance in CRC patients. This review
provides an overview of the intestinal stem cell markers leucine-rich repeat-containing G-
protein-coupled receptor 5 (LGR5), B cell–specific Moloney murine leukemia virus insertion …
cancers. Therefore, improved differential diagnostics and personalized treatment are still
needed. Several intestinal stem cell markers have been found to be associated with CRC
and might have a prognostic and predictive significance in CRC patients. This review
provides an overview of the intestinal stem cell markers leucine-rich repeat-containing G-
protein-coupled receptor 5 (LGR5), B cell–specific Moloney murine leukemia virus insertion …