[HTML][HTML] Moesin regulates the trafficking of nascent clathrin-coated vesicles

J Barroso-Gonzalez, JD Machado… - Journal of biological …, 2009 - ASBMB
Clathrin-coated vesicles are responsible for the trafficking of several internalized biological
cargos. We have observed that the endogenous F-actin-linker moesin co-distributes with
constitutive components of clathrin-coated structures. Total internal reflection fluorescence
microscopy studies have shown that short interference RNA of moesin enhances the lateral
movement of clathrin-coated structures and provokes their abnormal clustering. The
aggregation of clathrin-coated structures has also been observed in cells overexpressing N …