The dorsomedial hypothalamus and the central pathways involved in the cardiovascular response to emotional stress

MAP Fontes, CH Xavier, RCA De Menezes, JA DiMicco - Neuroscience, 2011 - Elsevier
Neuroscience, 2011Elsevier
Psychological stress elicits increases in sympathetic activity accompanied by a marked
cardiovascular response. Revealing the relevant central mechanisms involved in this
phenomenon could contribute significantly to our understanding of the pathogenesis of
stress-related cardiovascular diseases, and the key to this understanding is the identification
of the nuclei, pathways and neurotransmitters involved in the organization of the
cardiovascular response to stress. The present review will focus specifically on the …
Abstract
Psychological stress elicits increases in sympathetic activity accompanied by a marked cardiovascular response. Revealing the relevant central mechanisms involved in this phenomenon could contribute significantly to our understanding of the pathogenesis of stress-related cardiovascular diseases, and the key to this understanding is the identification of the nuclei, pathways and neurotransmitters involved in the organization of the cardiovascular response to stress. The present review will focus specifically on the dorsomedial hypothalamus, a brain region now known to play a primary role in the synaptic integration underlying the cardiovascular response to emotional stress.
Elsevier