Bombesin-induced hypothermia in rats tested at normal ambient temperatures: contribution of the sympathetic nervous system
C Barton, DA York, GA Bray - Brain research bulletin, 1995 - Elsevier
Rats infused centrally with bombesin become hypothermic at normal ambient temperatures
when acutely deprived of food, but not while allowed unrestrained access to food. Ad lib-fed
rats, tested at normal ambient temperatures, become hypothermic after receiving
intracerebroventricular (ICV) bombesin when they have ventromedial hypothalamic lesions
or when administered insulin or 2-deoxy-d-glucose peripherally. All of these conditions have
been linked to reductions of sympathetic nervous system activity to brown adipose tissue …
when acutely deprived of food, but not while allowed unrestrained access to food. Ad lib-fed
rats, tested at normal ambient temperatures, become hypothermic after receiving
intracerebroventricular (ICV) bombesin when they have ventromedial hypothalamic lesions
or when administered insulin or 2-deoxy-d-glucose peripherally. All of these conditions have
been linked to reductions of sympathetic nervous system activity to brown adipose tissue …
