Fracture burden and risk factors in childhood CKD: results from the CKiD cohort study
MR Denburg, J Kumar, T Jemielita… - Journal of the …, 2016 - journals.lww.com
Childhood chronic kidney disease (CHD) poses multiple threats to bone accrual; however,
the associated fracture risk is not well characterized. This prospective cohort study included
537 CKD in Children (CKiD) participants. Fracture histories were obtained at baseline, at
years 1, 3, and 5 through November 1, 2009, and annually thereafter. We used Cox
regression analysis of first incident fracture to evaluate potential correlates of fracture risk. At
enrollment, median age was 11 years, and 16% of patients reported a prior fracture. Over a …
the associated fracture risk is not well characterized. This prospective cohort study included
537 CKD in Children (CKiD) participants. Fracture histories were obtained at baseline, at
years 1, 3, and 5 through November 1, 2009, and annually thereafter. We used Cox
regression analysis of first incident fracture to evaluate potential correlates of fracture risk. At
enrollment, median age was 11 years, and 16% of patients reported a prior fracture. Over a …