Paternal alcohol exposure and dental-facial anomalies in offspring

D Vinayachandran, SK Balasubramanian - J Clin Invest, 2023 - Am Soc Clin Investig
Alveolar macrophages (AMs) are the sentinel cells of the alveolar space, maintaining
homeostasis, fending off pathogens, and controlling lung inflammation. During acute lung
injury, AMs orchestrate the initiation and resolution of inflammation in order to ultimately
restore homeostasis. This central role in acute lung inflammation makes AMs attractive
targets for therapeutic interventions. Single-cell RNA-Seq and spatial omics approaches,
together with methodological advances such as the generation of human macrophages from …

Paternal alcohol exposure and dental-facial anomalies in offspring/Reply

D Vinayachandran… - Journal of Clinical …, 2023 - search.proquest.com
To the Editor: We read with great interest the recent article by Thomas et al.(1), wherein the
authors shed light on an unexplored research hypothesis, highlighting the significant link
between paternal alcohol exposure and fetal alcohol syndrome (FAS). Considering the
seriousness with which alcohol use by women during pregnancy has been viewed, it is
noteworthy that there is no previous research evidence on the role of paternal alcohol
exposure in the development of craniofacial abnormalities and related growth …