[HTML][HTML] Cloning and characterization of a novel six-transmembrane protein STEAP2, expressed in normal and malignant prostate

KP Porkka, MA Helenius, T Visakorpi - Laboratory investigation, 2002 - Elsevier
By using subtraction and cDNA array hybridizations, we recently identified an anonymous
transcript that was differentially expressed in benign prostate hyperplasia and prostate
cancer cell line PC-3. Here, we report the cloning of the full-length cDNA of the gene,
designated STEAP2 (six-transmembrane epithelial antigen of the prostate 2). The gene is
located at the chromosomal region 7q21 and encodes for a 490–amino acid protein with six
predicted transmembrane domains and is predominantly expressed in prostate epithelial …