The prostate-specific membrane antigen: lessons and current clinical implications from 20 years of research
BT Ristau, DS O'Keefe, DJ Bacich - Urologic Oncology: Seminars and …, 2014 - Elsevier
Objective Despite a multitude of detection and treatment advances in the past 2 decades,
prostate cancer remains the second leading cause of deaths due to cancer among men in
the United States. Technological evolution and expanding knowledge of tumor biomarkers
have invigorated exploration in prostate cancer therapeutics. Prostate-specific membrane
antigen (PSMA) was one of the first prostate cancer biomarkers successfully cloned. Since
then, it has been characterized as the prototypical cell-surface marker for prostate cancer …
prostate cancer remains the second leading cause of deaths due to cancer among men in
the United States. Technological evolution and expanding knowledge of tumor biomarkers
have invigorated exploration in prostate cancer therapeutics. Prostate-specific membrane
antigen (PSMA) was one of the first prostate cancer biomarkers successfully cloned. Since
then, it has been characterized as the prototypical cell-surface marker for prostate cancer …
