A novel and simple method for culturing pericytes from mouse brain
U Tigges, JV Welser-Alves, A Boroujerdi, R Milner - Microvascular research, 2012 - Elsevier
Pericytes play critical roles in the development, maturation and remodeling of blood vessels,
and in the central nervous system (CNS), evidence suggests that pericytes also regulate
blood flow and form an integral part of the blood–brain barrier. The study of this important
cell type has been hampered by the lack of any pericyte-specific marker and by the difficulty
of culturing pericytes in adequate numbers to high purity. Here we present a novel yet
simple approach to isolate and culture large numbers of pericytes from the mouse CNS that …
and in the central nervous system (CNS), evidence suggests that pericytes also regulate
blood flow and form an integral part of the blood–brain barrier. The study of this important
cell type has been hampered by the lack of any pericyte-specific marker and by the difficulty
of culturing pericytes in adequate numbers to high purity. Here we present a novel yet
simple approach to isolate and culture large numbers of pericytes from the mouse CNS that …