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Clinical Medicine
Scientific Show Stopper
0 Articles
238 Posts
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A network of diuretic resistance
Richard Grimm and colleagues use a systems biology approach to uncover mechanisms of renal compensation that lead to diuretic resistance…
Published April 20, 2015
Scientific Show Stopper
Nephrology
Smothering Von Hippel-Lindau syndrome-associated phenotypes
Ana Metelo and colleagues demonstrate that specific inhibition of HIF2a ameliorates VHL-associated phenotypes and improves survival in a zebrafish model of disease…
Published April 13, 2015
Scientific Show Stopper
Oncology
Blazing the trail for metastasis
Jill Westcott, Amanda Prechtl, and colleagues identify an epigenetically distinct population of breast cancer cells that promotes collective invasion…
Published April 6, 2015
Scientific Show Stopper
Oncology
Intracellular calcium leak recasts β cell landscape
Gaetano Santulli and colleagues reveal that RyR2 calcium channels in pancreatic β cells mediate insulin release and glucose homeostasis…
Published April 6, 2015
Scientific Show Stopper
Metabolism
Synergy among Parkinson’s disease-associated genes
Durga Meka and colleagues demonstrate that crosstalk between parkin and RET maintains mitochondrial integrity and protects dopaminergic neurons…
Published March 30, 2015
Scientific Show Stopper
Neuroscience
Protecting retinal neurons with NRF2
Wenjun Xiong and colleagues demonstrate the viral-mediated introduction of antioxidant genes into the eyes of retinitis pigmentosa mice protects cones from degeneration...
Published March 23, 2015
Scientific Show Stopper
Dynamic focal adhesions
Wies van Roosmalen, Sylvia E. Le Dévédec, and colleagues screen for genes that alter cancer cell migration and demonstrate that SRPK1 promotes metastasis...
Published March 16, 2015
Scientific Show Stopper
Oncology
KIM-1 protects the kidney after injury
Li Yang, Craig Brooks, and colleagues at Harvard Medical School demonstrate that KIM-1-mediated phagocytosis of apoptotic cells dampens inflammatory responses after kidney injury.. .
Published March 9, 2015
Scientific Show Stopper
Nephrology
A family affair
Vijay Sankaran and colleagues demonstrate that a mutation in the X-chromosomal gene encoding aminolevulinic acid synthase underlies disease in a family with macrocytic anemia…
Published February 23, 2015
Scientific Show Stopper
Hematology
Attack of the WNT inducing macrophages
Luke Boulter and colleagues reveal that WNT ligand-secreting macrophages promote cholangiocarcinoma proliferation….
Published February 17, 2015
Scientific Show Stopper
Oncology
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